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RETINOL: Tretinoin 101Updated 2 days ago

Q: Is Tretinoin the best option for anti-aging?

A. While tretinoin (prescription retinoic acid) has been shown to support youthful skin, at AOS we find that it’s often too harsh for most skin types. Over time, tretinoin can weaken the skin barrier and trigger chronic inflammation — which actually accelerates aging.

Instead, we recommend professional-strength retinols that are:
✔️ Gentler on the skin barrier
✔️ Combined with peptides, antioxidants, and brighteners
✔️ Designed to firm, smooth, and brighten without excessive irritation

This gives you the benefits of retinol — like increased collagen and smoother skin — without unnecessary inflammation or damage.

Barrier-Friendly Retinols

Sensitive Skin: NeoGenesis Recovery Serum 

Menopausal Skin: Emepelle Night Cream

Best All Around / AOS Innovation Award Winner: iS Clinical Retinol+ Emulsion 0.3%

Best Retinol Alternative with Retinal, Bakuchiol, and Vitamin C / AOS Innovation Award Winner: Sorella Apothecary Resurfacing Elixir 


👉 Need help choosing? Get a Free Skincare Check up with an AOS esthetician!

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